With 14 faculty members listed among the new 2004-05 American Association for the Advancement of Science Fellows, Ohio State now boasts 90 Fellows. Among these newest inductees is Ching-Shih Chen, professor of Medicinal Chemistry at the OSU College of Pharmacy, cited "for fundamental studies of lipid-mediated signal transduction pathways in cancer and for discovery of novel therapeutic agents that modulate cancer cell activation and death." Chen's work merges synthetic organic chemistry with molecular and cellular biology to design novel chemotherapeutic agents that attack molecular defects in tumor cells. Currently, many of these promising compounds are undergoing tests at different laboratories in the Ohio State University Comprehensive Cancer Center to evaluate their effectiveness against a number of cancers -- including prostate, breast, lung, pancreatic, and ovarian cancers, and chronic lymphocytic leukemia.
Other faculty in the College of Pharmacy who are AAAS Fellows include Jessie Lai-Sim Au, Robert W. Brueggemeier, John M. Cassady, Popat N. Patil, Wolfgang Sadee and M. Guillaume Wientjes.

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