College of Pharmacy Research Day 2008: List of Research Projects

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List of selected Research Day abstracts

01 COMPUTATIONAL MODELS OF THE MECHANISMS BY WHICH ANTIPSYCHOTIC DRUGS INCREASE EXTRACELLULAR DOPAC
   Bonfiglio, Wallace

02 AN ASSESSMENT OF PHARMACIST AND PATIENT KNOWLEDGE OF & ATTITUDES TOWARD REPORTING ADVERSE DRUG REACTIONS IN PATIENTS WITH EPILEPSY
   A Chen, McAuley

03 THE SYNTHESIS OF GdB-TEXPHYRINS AS NOVEL MULTIPURPOSE CANCER DRUGS
   Jordan, Narayanasamy, Tjarks

04 AMINOGLYCOSIDE DOSING AND PHARMACOKINETICS IN OVERWEIGHT AND OBESE PEDIATRIC PATIENTS
   Kusick, Sargel

05 ASSESSING THE ROLE OF THE PHARMACIST IN THE CARE OF PATIENTS WITH EPILEPSY
   M Miller, McAuley

06 ENHANCING THE CARE OF PREGNANT WOMEN WITH EPILEPSY: A FOCUS GROUP
   Patankar, McAuley

07 EFFECTS OF AMPHETAMINE ON DOPAMINE AND ITS METABOLITES: A COMPUTATIONAL MODEL
   Russell, Wallace

08 DIFFERENTIAL EXPRESSION OF THE GLUCOSE TRANSPORTER PROTEIN ACROSS CARDIAC REGIONS IN NORMAL HEARTS AND DURING HEART FAILURE
   Ware, Bevier, Nishijima, Sridhar, Carnes, Lacombe

09 ANTIOXIDANT CONSTITUENTS FROM THE LEAVES OF PELARGONIUM CITROSUM
   Zorko, J Kim, Lau, Tay, Carcache de Blanco

10 IN VITRO AND IN VIVO STUDIES OF A NOVEL INDOLE WITH POTENT ANTIMITOTIC ACTIVITY IN PROSTATE CANCER AND DRUG-RESISTANT TUMORS
   Ahn, Duke III, Hwang, D Miller, Dalton

13 MEASURING MEDICATION ADMINISTRATION ERRORS IN DIFFERENT SETTINGS
   Bellebaum, P Schneider, Curran, Salsberry, McAuley, Pedersen

14 EVALUATING THE USE OF PROVISIONAL PATENTS BY THE PHARMACEUTICAL INDUSTRY: THE EXPERIENCE OF THE UNITED STATES
   Beyer, Visaria, Seoane-Vazquez, Szeinbach

15 COMPARISON OF PHARMACY PRACTICE IN VETERANS AFFAIRS HOSPITALS AND GENERAL/CHILDREN'S MEDICAL-SURGICAL HOSPITALS: RESULTS FROM THE 2004, 2005 AND 2006 ASHP NATIONAL SURVEYS
   E Chang, P Schneider, Scheckelhoff, Torrise, Pedersen

16 COMPUTATIONAL DESIGN OF STAT3 INHIBITORS FOR TARGETED ANTI-CANCER THERAPY
   Cisek, Bhasin, Regan, Friedman, Sobo, J Lin, Tom P-K Li, C Li

18 SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF CURCUMIN ANALOGUES
   Etter, Fuchs, Tom P-K Li, Abdelhamid, Regan, Bhasin, Pandit, C Li, Cisek, Cen, Hutzen, Lin

20 DETERMINANTS OF NANOPARTICLE TRANSPORT IN TUMORS: A COMPUTATIONAL MODEL
   Au, Gao, B Chen, Z Shen, Wientjes

21 TRANSCRIPTIONAL REPRESSION OF ANDROGEN RECEPTOR BY THE α-TOCOPHERYL SUCCINATE DERIVATIVE TS-1 IN PROSTATE CANCER CELLS
   P-H Huang, Hung, Chuang, S Wei, Kulp, C-S Chen

22 ENHANCING THE EFFECTIVENESS OF COMMUNITY STROKE RISK SCREENING: A RANDOMIZED CONTROL TRIAL
   Anderson, Camacho, Kharbanda, Iaconi, Balkrishnan

23 γH2AX AS PHARMACODYNAMIC MARKER IN DNA-DAMAGING TREATMENT
   Ji, Y Wei, M Liu, Z Shen, T Shen, Wientjes, Au

24 PRE AND POST STROKE STATIN USE AND ASSOCIATED HEALTH CARE COSTS AMONG ELDERLY STROKE SURVIVORS
   Karve, Levine, Balkrishnan

25 PHYSICIAN AND PATIENT CHARACTERISTIC IN AMBULATORY CARE UTILIZATION RELATED TO STROKE: ANALYSIS OF THE NATIONAL AMBULATORY MEDICAL CARE SURVEY DATA 2000-2005
   Karve, Levine, Balkrishnan

26 DEVELOPMENT OF AN LC/MS/MS ASSAY FOR SIMULTANEOUSLY DETERMINING METABOLIC STABILITY OF 2-ARYLTHIAZOLIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES
   C-M Li, Y Lu, Phelps, D Miller, Dalton

27 NONTOXIC DOSES OF SURAMIN ENHANCES CHEMOTHERAPY IN PANCREATIC XENOGRAFT TUMORS
   J Li, T Shen, J Wang, Au, Wientjes

28 POST-TRANSCRIPTIONAL REGULATION OF INDUCIBLE NITRIC OXIDE SYNTHASE (iNOS) BY PROTEIN INTERACTING WITH NEVER IN MITOSIS GENE A-1 (PIN1) IN MURINE AORTIC ENDOTHELIAL CELLS
   T Liu, Likhotvorik, Y Huang, Keshvara, D Hoyt

29 COMPLEX EFFECTS OF DIMETHYLBIGUANIDE ON NEURONAL BIOENERGETICS IN VITRO
   Ma, Carrier, Kirry, K Hoyt

30 CELLULAR COFACTOR LEDGF PROFOUNDLY AFFECTS HIV-1 INTEGRASE SUBUNIT-SUBUNIT INTERACTIONS
   McKee, Kessl, Dar, Engelman, Musier-Forsyth, Kvaratskhelia

31 NOVEL LIGAND-INDUCED-FIT SIMULATION OF SURVIVIN VIA REPLICA EXCHANGE MOLECULAR DYNAMICS (REMD) AND RECEPTOR-BASED ENSEMBLE DOCKINGS
   I-H Park, C Li

32 ANTISENSE INHIBITION OF MICRORNA ARRESTS CELL CYCLE, INDUCES APOPTOSIS AND SENSITIZES THE EFFECTS OF GEMCITABINE IN PANCREATIC CANCER
   J-K Park, E-J Lee, Esau, Schmittgen

33 PREDICTORS OF MEDICATION ADHERENCE IN OLDER ADULTS WITH INSOMNIA
   Kulkarni, I Patel, Anderson, Balkrishnan

34 DEPRESSIVE SYMPTOMATOLOGY, MEDICATION PERSISTENCE, AND ASSOCIATED HEALTHCARE COSTS IN OLDER ADULTS WITH INSOMNIA
   Kulkarni, I Patel, Anderson, Balkrishnan

35 MODELING NICOTINIC ACETYLCHOLINE RECEPTORS FOR COMPUTATIONAL INHIBITOR DESIGN
   Pavlovicz, C Li

36 MARKET DISCONTINUATION OF PHARMACEUTICALS IN THE UNITED STATES: ANALYSIS OF NEW DRUGS APPROVED FROM 1980 TO 2007
   Qureshi, Szeinbach, Seoane-Vazquez

37 INDIVIDUAL AND COMBINATIONAL EFFECTS OF ESTROGEN REGULATION ENZYME INHIBITORS IN HUMAN BREAST CANCER CELLS
   Rich, Tom P-K Li, Brueggemeier

38 THE HDAC INHIBITOR OSU-HDAC42 BLOCKS THE PROGRESSION OF SPONTANEOUS PROSTATE CANCER AND ENHANCES DIFFERENTIATION IN PART THROUGH UPREGULATION OF E-CADHERIN
   Sargeant, Rengel, Kulp, Yeater, Clinton, Y-C Wang, C-S Chen

39 DEPLETION OF PROTEIN INTERACTING WITH NEVER IN MITOSIS GENE A-1 (PIN1) DECREASES MAMMARY ADENOCARCINOMA CELL GROWTH IN CULTURE, BUT INCREASES VEGF AND TUMOR GROWTH IN MICE
   R Schneider, T Liu, Y Huang, Keshvara, D Hoyt

40 ?-GLUCAN INDUCED MICROGLIAL ACTIVATION THROUGH DECTIN-1 IS DEVOID OF CYTOKINE PRODUCTION
   Shah, Keshvara

41 COMPUTATION-BASED CLINICAL DEVELOPMENT: IMPROVING EFFICACY OF INTRAVESICAL CHEMOTHERAPY OF BLADDER CANCER
   T Shen, Z Shen, Badalment, Young, Venema, Pollifrone, Harbrecht, J Chin, Lerner, Miles, Wientjes, Au

42 INTEGRIN ENGAGEMENT REDUCES APE1 CO-IMMUNOPRECIPITATION WITH XRCC1 IN HYDROGEN PEROXIDE-TREATED MURINE LUNG ENDOTHELIAL CELLS
   Stevens, D Hoyt

43 TRENDS IN EPISODE OF TREATMENT COSTS OF ACNE ACROSS THE UNITED STATES
   Balkrishnan, Uhas, Reese, Feldman

44 IS THERE AN ACCEPTABLE LEVEL OF MEDICATION ADHERENCE? A REVIEW OF RETROSPECTIVE ADHERENCE EVALUATION STUDIES
   Visaria, Seoane-Vazquez, Schwartzbaum, Szeinbach

45 25 YEARS OF ORPHAN DRUG ACT: ANALYSIS OF THE NEW ORPHAN DRUGS APPROVED BETWEEN 1983 AND 2007
   Visaria, Rodriguez-Monguio, Seoane-Vazquez

46 A NOVEL MECHANISM BY WHICH THIAZOLIDINEDIONES FACILITATE THE PROTEASOMAL DEGRADATION OF CYCLIN D1
   S Wei, H-C Yang, Chuang, Jian Yang, Kulp, P-J Lu, Lai, C-S Chen

47 INDUCTION OF HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 DEGRADATION BY CELECOXIB AND ITS DERIVATIVE OSU-03012
   Weng, C-S Chen

48 EFFECTS OF COMORBID HYPERLIPIDEMIA ON OUTCOMES ASSOCIATED WITH TYPE 2 DIABETES TREATMENTS IN TWO POPULATIONS
   Wu, Balkrishnan

49 PHARMACOLOGICAL EXPLOITATION OF THE PPARg AGONIST CIGLITAZONE TO DEVELOP A NOVEL CLASS OF ANDROGEN RECEPTOR-ABLATIVE AGENTS
   Jian Yang, S Wei, D-S Wang, Y-C Wang, Kulp, C-S Chen

50 COMPUTATIONAL MODELING TO EVALUATE THE CONTRIBUTION OF AN INDIVIDUAL MECHANISM TO THE ACTION OF A MULTI-TARGET AGENT: INTERACTION OF SURAMIN WITH PACLITAXEL
   Jianning Yang, L Zhao, Wientjes, Au

51 TRANSFERRIN RECEPTOR-TARGETED LIPOPOLYPLEXES FOR DELIVERY OF A BCL-2-SPECIFIC ANTISENSE OLIGODEOXYRIBONUCLEOTIDE (G3139) TO LEUKEMIA
   X Yang, Koh, S Liu, Yu, Peng, X Pang, Golan, Talmon, Byrd, L J Lee, Marcucci, R Lee

53 SYNTHESIS AND BIOLOGICAL EVALUATION OF ORYZALIN AND TRIFLURALIN ANALOGS AGAINST MALARIA AND TOXOPLASMA PARASITES
   Endeshaw, Latibeaudiere, Mahasenan, C Li, Morrissette, Kyle, Werbovetz

54 TARGETED DELIVERY OF OLIGONUCLEOTIDES FOR ANTI-LEUKEMIA THERAPY USING MULTIFUNCTIONAL IMMUNOLIPOPOLYPLEX NANOCARRIERS
   Y Jin, Yu, S Liu, Zhang, Lapalombella, Triantafillou, Pang, Muthusamy, L J Lee, Byrd, Marcucci, R Lee

55 ISOLATION OF BIOACTIVE COMPONENTS FROM THE LEAVES OF FOENICULUM VULGARE (APIACEAE)
   Kim, Lau, Tay, Carcache de Blanco

56 ISOLATION OF ANTIOXIDANT COMPONENTS FROM THE LEAVES OF PELARGONIUM GRAVEOLENS (GERANIACEAE)
   Kim, Lau, Tay, Carcache de Blanco

57 IMPACT OF A PHARMACIST'S EDUCATIONAL INTERVENTION ON PATIENT KNOWLEDGE REGARDING ANTIDEPRESSANT USE
   Lundstrom, Green, Beatty, Clark, McAuley

58 PERCEPTIONS OF PHYSICIANS REGARDING DIABETES EDUCATION AND MANAGEMENT
   Metzger, Lamb, Pruchnicki, Beatty

59 SYNTHETIC STUDIES OF SPIRO [CYCLOALKANE-1, 3'-INDOLENINE] DERIVATIVES
   Narayanasamy, Schwartz, P Patel, Fuchs

61 SAFETY AND EFFICACY OF INHALED AMINOGLYCOSIDES IN MECHANICALLY VENTILATED PREMATURE INFANTS FOR THE TREATMENT SYMPTOMATIC GRAM-NEGATIVE BACILLI TRACHEITIS
   Phan, Pai, Puthoff, Nahata

62 ASSESSMENT OF BASIC KNOWLEDGE AMONG CHILD CARE PROVIDERS REGARDING GENERAL PEDIATRIC HEALTH CARE AND PHARMACOTHERAPY, ASTHMA, AND DIABETES MELLITUS
   Phan, Pai, Mehta, Reschke, McDowell, Cable, Nahata

63 ERYTHROPOIETIN AND THE RISK OF SEVERE RETINOPATHY IN EXTREMELY LOW BIRTH WEIGHT INFANTS
   J Schneider, Gardner, Cordero

64 DETERMINING FACTORS THAT INFLUENCE PATIENT PARTICIPATION IN MEDICATION THERAPY MANAGEMENT SERVICES
   Sullivan, Casper, Green

65 ACCURACY OF WRITTEN MEDICATION RECORDS IN AN ACADEMIC FAMILY PRACTICE CENTER
   Vinh, Coyle, Brackett

66 ELISA AND PK FOR SYNTHETIC MIRNAS
   Xie, Z Liu, Chiu, Dunkerson, Muthusamy, Garzon, S Liu, Croce, Byrd, Marcucci, K Chan

67 MEDICATION PERSISTENCE AND ASSOCIATED HEALTH CARE COSTS IN AN OLDER POPULATION WITH DEMENTIA: A LONGITUDINAL COHORT STUDY
   Balkrishnan, Kong, Bonza, Anderson

68 INTRODUCTION OF A SIMULATED ELECTONIC MEDICAL RECORD TO A PHARMACY CURRICULUM
   Beatty, Legg, Gladden
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69 MECHANISTIC STUDIES OF THE NONYDROLYSABLE RETINOID ANALOG, 4-HYDROXYBENZYL- RETINONE (4-HBR)
   Curley, Clagett-Dame, Alshafie

70 CHROMOSOME 21-DERIVED MIR-155 PROVIDES AN ETIOLOGIC BASIS FOR ABERRANT PROTEIN EXPRESSION IN HUMAN DOWN SYNDROME BRAINS
   Kuhn, Nuovo, Martin, Malana, Pleister, Gardiner, Terry Jr, Head, Lott, Elton, Feldman

71 ENHANCEMENT OF THE RATE OF SOLUTION OF RELATIVELY INSOLUBLE DRUGS FROM SOLID-SOLID SYSTEMS PREPARED BY SUPERCRITICAL FLUID TECHNOLOGY
   Ramirez, Frank

72 DESCRIPTION OF AND DOCUMENTED PHARMACIST INTERVENTIONS FROM A FIVE-YEAR COLLABORATION AIMED AT ENHANCING THE CARE OF PREGNANT WOMEN WITH EPILEPSY
   McAuley, Shneker, Moore, Long, Prasad, Samuels

73 IMPACT OF TECHNOLOGY-BASED CASE CONFERENCE WORKSHOP ON STUDENT LEARNING, PROBLEM SOLVING SKILLS AND SATISFACTION
   Pai, Kelley

74 DELAYED ADMINISTRATION OF FILGRASTIM (G-CSF) FOLLOWING AUTOLOGOUS PERIPHERAL BLOOD STEM CELL TRANSPLANT (APBSCT) IN PEDIATRIC PATIENTS DOES NOT CHANGE TIME TO NEUTROPHIL ENGRAFTMENT AND REDUCES USE OF G-CSF
   Pai, Fernandez, Laudick, Rosselet, Termuhlen

75 COMPARISON OF GLOMERULAR FILTRATION RATE (GFR) BY THREE METHODS IN PEDIATRIC ONCOLOGY PATIENTS
   Pai, Miller, Soni, Novak

76 EFFICACY AND SAFETY OF OCTREOTIDE ACETATE IN TREATING CHEMOTHERAPY OR ACUTE GRAFT VERSUS HOST DISEASE INDUCED DIARRHEA IN PEDIATRIC ONCOLOGY PATIENTS
   Pai, E Yang

77 ELECTRON MICROSCOPIC STUDIES OF THE IRIS PIGMENT IN RELATION TO THE DRUG ACTION
   Patil, Salazar-Bookaman, Ishikawa

78 PARTNER FOR PROMOTION: AN INNOVATIVE APPROACH TO PRACTICE, RESEARCH, AND TEACHING IN A COMMUNITY PHARMACY
   Rodis, Casper, Legg

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