Hickman MA, Malone RW, Lehmann-Bruinsma K, Sih TR, Knoell DL, et al. Gene expression following direct injection of DNA into liver. Human Gene Therapy 1994 5:1477-1483.
Wadhwa MS, Knoell DL, Young AP, Rice KG. Targeted gene delivery with a low molecular weight glycopeptide carrier. Bioconjugate Chemistry 1995 6:283-291.
Knoell DL, Wewers MD. Clinical implications of gene therapy for alpha-1-antitrypsin deficiency. Chest 1995 107(2):535-545.
Kunzelmann K., Legendre JY., Knoell DL., Escobar LC., Xu Z., Gruenert DC. "Gene Targeting of CFTR DNA in CF Epithelial Cells." Gene Therapy, 1996 3:859-867.
Knoell DL., Marsh CB. "Vocal Cord Dysfunction Presenting as "Steroid-Dependent" Asthma. Journal of Pharmacy Technology, 1997; 13:118-121. (corresponding author)
Knoell DL., Ralston D., Coutler KR., Wewers MD. Alpha 1-antitrypsin and protease complexation is induced by lipopolysaccharide, Interleukin-1b, and tumor necrosis factor-a in monocytes. American Journal of Respiratory Disease and Critical Care Medicine. 1998;157:246-255. (corresponding author)
Marsh CB., Lowe MP., Rovin BH., Liao Z, Knoell DL., Wewers MD. Lymphocytes produce IL-1b in response to Fcg receptor cross-linking: Effects on parenchymal cell IL-8 release. Journal of Immunology. 1998;160:3942-3948.
Knoell DL., Yiu I. A review of reported clinical data from human gene trials treating hereditary diseases. American Journal of Health-System Pharmacists. 1998;55:899-904.
Knoell DL., Lucas JG., Allen JA. Churg-Strauss syndrome associated with zafirlukast. Chest. 1998;114:332-334.
Knoell DL., Pierson JF., Marsh CB., Allen JA., Pathak DS. Measurement of outcomes in adult patients receiving pharmaceutical care in a comprehensive asthma outpatient clinic. Pharmacotherapy. 1998;18(6):1365-1374. (corresponding author)
Knoell DL. Clinical aspects of gene therapy. Annals of Pharmacotherapy. 1998;32:977-979.
Coulter KR, Wewers MD., Lowe MP., Knoell DL. Extracellular regulation of interleukin-1 beta through lung epithelial cells and defective interleukin-1 type II receptor expression. American Journal of Respiratory Cell and Molecular Biology. 1999:20(5):964-975. (corresponding author)
Knoell DL, Marsh CB. Vocal cord dysfunction and steroid-dependent asthma. Respiratory Diseases Review Series. 1999:3;118-121.
Coulter K., Allen ED, Hart J, Wewers MD, Castile RG, Knoell DL. Induction of interleukin-8 by lung epithelium with cystic fibrosis epithelial lining fluid is marginally affected by inhibitors of IL-1b. Pharmacotherapy: 2000;20(1):64-74. (corresponding author)
Bayat M, Davis L, Knoell DL, Korth-Bradley J, Munger M, Schaefer M, Vlasses P, Wermling D, Ujhelyi M. The clinical pharmacist as principal investigator. A white paper on behalf of the American College of Clinical Pharmacy. Pharmacotherapy. 2000;20(5):599-608.
Knoell DL, Coulter KR, Doseff A, Wewers MD. Opposing effect of cytokines on Fas-mediated apoptosis in lung parenchymal cells.American Journal of Respiratory Cell and Molecular Biology)(corresponding author). in press.
Swaan PW, Knoell DL, Helsper F, Wewers MD. Sequential Processing of Human ProIl-1b by Caspase-1 and Subsequent Folding Determined by a Combined In Vitro and In Silico Approach. Pharmaceutical Research 2001;18(8):20-30.
Knoell DL, Coulter KR, Carter JE, Nuovo G, Wewers MD. The lung epithelium is a reservoir for M-trophic HIV-1 infection. Manuscript in preparation. (Corresponding Author).
Recent Abstracts:
Coulter KR, Knoell DL. Increased expression of the interleukin-1 type II receptor in a murine model of acute lung inflammation. Pharmacotherapy. 1998;18:A173.
Knoell DL, Coulter KR. Regulation of IL-1b through lung epithelial cells and defective interleukin-1 type II receptor expression. Pharmacotherapy. 1998;18:A169.
Pierson JF., Knoell DL., Pathak DS., Marsh CB., Allen JN. Pharmaceutical care in a comprehensive asthma clinic. Pharmacotherapy. 1998;18:A221.
Coulter KR, Doseff A, Knoell DL. Lung epithelial cells constitutively express caspase activity which is augmented by IL-1b and IFNg. American Journal of Respiratory and Critical Care Medicine. 1999;159(3):A907.
Wade J., Coulter KR., Wewers MD., Mehta V., Knoell DL. The lung epithelium is a souce of IL-18 but release is tightly regulated by cytokines and ATP. American Journal of Respiratory and Critical Care Medicine. 2000;161(4):J118.
Coulter KR., Knoell DL. Interleukin-1b protects A549 lung epithelial cells from apoptosis. American Journal of Respiratory and Critical Care Medicine. 2000;161(4):J119.
Knoell DL., Swaan P., Helsper F., Wewers MD. Sequential processing of interleukin-1b by caspase-1 (ICE): A model based upon the structure of a1-antitryupsin (a1-AT). American Journal of Respiratory and Critical Care Medicine. 2000;161(4):J118.
Knoell DL., Coulter K., Carter J., Wewers MD. Infection of human lung epithelial cells by M-trophic HIV-1. American Journal of Respiratory and Critical Care Medicine. 2001;163(5):A285
Elssner A., Carter J., Knoell D., Wewers MD. Co-culture with lung epithelial cells inhibits HIV-1 infection of monocyte derived macrophages. American Journal of Respiratory and Critical Care Medicine. 2001;163(5):A285.
Sweeney P., Wang Y., Marsh C., Knoell DL. Keratinocyte Growth Factor prevents apoptosis in A549 lung epithelial cells and induces Akt kinase activity. Presented as poster at the Lovelace Respiratory Research Institute International Symposium: Remodeling and Repair in Respiratory Diseases. Santa Fe, NM 2001.
Coulter K., Doseff A., Wewers MD., Knoell DL. Opposing Effect by Cytokines on Fas-Mediated Apoptosis in Lung Parenchymal Cells. Amer J Resp Cell Mol Biol. 2002;26:58-66.
Johnson J., Bootman J., Evans W., Hudson R., Knoell D., Simmons L., Straubinger R., Meyer S. Pharmacogenomics: A scientific revolution in pharmaceutical sciences and pharmacy practice. Amer J Pharm Edu. 2002;66:12S-15S.
Knoell DL and Spector S. Minimizing the impact of inadequately controlled moderate to severe asthma. Journal of Managed Care. February 2004:38-43.
Yearsley M, Knoell DL, Diaz PT, Nuovo G. Correlation of HIV-1 detection and histology in AIDS-associated emphysema Diagnostic Molecular Pathology. 2005;14(1):48-52.
Sweeney P., Wang Y., Chaudhuri A., Doseff AI., Marsh CB., Knoell DL. Keratinocyte Growth Factor induces Akt kinase and inhibits Fas-mediated apoptosis in A549 lung epithelial cells. Amer J Phys Lung Cell Mol Physiol. 2005;288:L36-42.
Bahadduri P, D’Souza R, Pinsonneault J, Sadee W, Knoell D, Swaan P. Functional characterization of PepT2 transporter in primary human lung epithelial cells. Amer J Resp Cell Mol Biol. 2005:32:1-7.
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