Division of Pharmacology: News Archive 2006-2007

Dr. Wallace Receives Distinguished Teaching Award

photo of Dr. Wallace

Dr. Lane J. Wallace has been awarded the 2007 Award for Distinguished Teaching in the Bachelor of Science in the Pharmaceutical Sciences (BSPS) Program.  This award is given to one faculty member in the College of Pharmacy each year to recognize outstanding teaching in the BSPS program. The recipient is selected via a ballot of currently enrolled BSPS students. The recipient is honored at a special student assembly prior to Spring Commencement. The recipient receives a cash honorarium and recognition plaque.

The Division of Pharmacology is extremely proud to have two members of its faculty that the students have chosen to award.  Congratulations to both Dr. Wallace & Dr. Keshvara!

Dr. Keshvara Receives Distinguished Teaching Award

photo of Dr. Keshvara

Dean Brueggemeier announced Friday, May 11th that Assistant Professor, Lakhu Keshvara, Ph.D., is this year's recipient of the Miriam R. Balshone Memorial Award for Distinguished Teaching. This award is given to one faculty member in the College of Pharmacy each year to recognize outstanding teaching in the Doctor of Pharmacy (PharmD) program. The recipient is selected via a ballot of currently enrolled PharmD students. The recipient is recognized at the annual Doctoral Convocation and Hooding Ceremony prior to Spring Commencement. The recipient receives a cash honorarium and recognition plaque. Congratulations Dr. Keshvara!

Dr. McKay publishes new journal article in the May issue of Molecular Pharmacology

photo of Dr. Patil

Professor Dennis McKay's research is featured on the cover of the May issue of Molecular Pharmacology.  His article titled, 'Analogs of methyllycaconitine as novel noncompetitive inhibitors of nicotinic receptors: pharmacological characterization, computational modeling, and pharmacophore development', can be found on page 1288: http://molpharm.aspetjournals.org/ Co-authors include Susan McKay, Tatiana Gonzalez-Cestari, Darrell Bryant and Raed El-Hajj.

About the cover: Overall alignment of all 67 compounds used in generating 3D-QSAR models.


Dr. Patil publishes new journal article in Autonomic & Autocoid Pharmacology

photo of Dr. Patil

Congratulations to Popat N. Patil, PhD for the July publication of:

Antagonism by imidazoline-type drugs of muscarinic and other receptors in the guinea-pig ileum.  M. M. Salazar-Bookaman, D. D. Miller & P. N. Patil. Autonomic & Autocoid Pharmacology, 26(3): 267-73, 2006

View the abstract here


The Division of Pharmacology presented 4 abstracts at the Society for Neuroscience Meeting, October 14-18, 2006 in Atlanta, GA.

Dr. Kari Hoyt & Graduate Student, Raeann Carrier, presented 'Bioenergetics in Huntington's disease transgenic neurons'.  Dr. Kari Hoyt & Graduate Student, Thong Ma, presented 'Free 3-nitrotyrosine impairs mitochondrial function in neurons'.  Dr. Lane J. Wallace presented 'A computational study of the effects of amphetamine on dopaminergic storage vesicles'.  And Dr. Dennis B. McKay, Susan McKay and Tatiana Gonzalez along with Dr. Robert T. Boyd and Dr. Michael X. Zhu (all from OSU) presented 'Interactions of noncompetitive antagonists with α3β4 neuronal nicotinic receptors: modeling of a negative allosteric binding site'.


BSPS Student Awarded Undergraduate Research Fellowships

Adam Kirry, an OSU BSPS student, was awarded one of four national individual Summer Undergraduate Research Fellowships from the American Society for Pharmacology and Experimental Therapeutics.  His fellowship helps support his Honors research project on mechanisms of neuronal cell death in Parkinson's disease with Dr Kari Hoyt in the Division of Pharmacology.  Congratulations Adam! 


The Division of Pharmacology presented 3 abstracts at the 15th World Congress of Pharmacology (IUPHAR, 2006) July 2-7th in Beijing, China. 

Dr. Hu presented 'Mechanism of K+ Channel Opener-mediated Cardioprotection'.  Dr. Patil (Jack Fowble, co-author) presented 'NMR and Pharmacologic Studies on the New Melanin from Bacillus thuringiensis' and 'History of Drugs: A Teaching Proposal at Universities'.


Pharmacology Post-Doc Wins Award at Poster Competition at EB2006

The American Society for Pharmacology and Experimental Therapeutics, Division of Neuropharmacology, hosted a poster competition at the Experimental Biology, 2006, meeting recently held in San Francisco.

First place in the Post-Doctoral Competition went to Dr. R. Benjamin Free, NIH/NINDS (sponsor: Dr. David Sibley). His presentation was entitled, “The chaperone protein calnexin regulates cell surface expression of both D1 and D2 dopamine receptors.". As a first place winner, Ben will be invited to serve on the Executive Committee for the next year and will receive $500.

Ben received his Ph.D. in Pharmacology (advisor, D.B. McKay) in 2002.

Ben is currently a Research Fellow in the Molecular Neuropharmacology Section, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD


The Division of Pharmacology presented 3 abstracts at the Society for Neuroscience annual meeting in Washington, DC, November 12-16, 2005.


R.L. Carrier, T.C. Ma, K Obrietan, K.R. Hoyt. A SENSITIVE AND SELECTIVE ASSAY OF NEURONAL DEGENERATION IN CELL CULTURE


T.C. Ma, K.R. Hoyt. SENSITIZATION TO NEURONAL EXCITOTOXICITY BY 3-NITROTYROSINE


L.J. Wallace, L.T. Pham COMPUTATIONAL SIMULATIONS OF THE IMPACT OF INHIBITION OF NEURON FIRING ON DOPAINERGIC VARICOSITIES OF THEDORSAL STRIATUM SUGGEST THAT STORAGE VESICLES ARE LEAKY



Congratulations to R. Benjamin Free, Susan B. McKay, Paul D. Gottlieb, R. Thomas Boyd, and Dennis B. McKay for the June publication of:

Expression of native a3b4* neuronal nicotinic receptors: binding and functional studies investigating turnover of surface and intracellular receptor populations. Molecular Pharmacology 67:2040-2048, 2005.



Congratulations to Dr. Mandar Joshi on the defense of his PhD thesis this August!

Mandar's thesis presentation was entitled "Mechanisms of Nitric Oxide Control in Endothelial and Cardiac Dysfunction " and his thesis advisor was Dr. John Bauer.


Congratulations to Dr. Shawn Pierson on the defense of his PhD thesis this March!

Shawn's thesis presentation was entitled "PACAP38 up-regulates nitric oxide synthase 1 expression via multiple signalling pathways" and his thesis advisor was Dr. Anthony Young.


Congratulations to Dr. Jane Rose on the defense of her PhD thesis this February!

Jane's thesis was entitled "Integrin-mediated alterations in chromatin and DNA repair proteins" and her thesis advisor was Dr. Dale Hoyt.


Dr. Dale Hoyt's lab presented several abstracts at the Experimental Biology
Meetings in San Diego, CA, April 2-5, 2005

Rose, J., H. Huang, Likhotvorik, RI, Hoyt, DG: Integrin-engagement
activates DNA ligase in murine lung endothelial cells.
Jane Rose's presentation was one of eleven abstracts selected by the American Society for
Investigative Pathology for special presentation in Highlight's of
Graduate Student Posters, April 2, 2005.

Huang, H., R. Stevens, Hoyt, DG: High-fat diet synergizes with endotoxin
and interferon-gamma to induce pro-inflammatory gene expression in various
murine tissues in vivo.
Rachel Stevens was a recipient of a College of Pharmacy Summer
Undergraduate Research Fellowship to conduct this research.

Huang, H., R. Buerki, Likhotvorik, RI, Hoyt, DG: The role of serine 727
and proline 728 in signal transducer and activator of transcription-1.
Hong Huang was selected for oral presentations for each of these
subjects. Robin Buerki was a recipient of the American Heart Association
Summer Undergraduate Research Fellowship, 2004, for this research.


Dr. Dale Hoyt's lab will present several abstracts at the annual meeting of the
American Thoracic Society/American Lung Association in San Diego, CA, May
21-25, 2005:

Rose, J., R. Likhotvorik, Hoyt, DG: Role Of Histone H3 Acetylation In The
Effects Of Integrin-Engagement On Histone-Promoter DNA Interaction In
Murine Lung Endothelial Cells.

Rose, J., K. Reeves, Hoyt, DG: DNA Ligase III is Required for
Integrin-Mediated Suppression of Bleomycin-Induced DNA Damage in Murine
Lung Endothelial Cells.
Kevin Reeves, Honors Student, was a recipient of a College of
Pharmacy Undergraduate Research Scholarship to conduct this research.

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