Topic titles link to abstracts
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Chung-Wai Shiau, Ph.D., 2005
Advisor: Chen, Ching-Shih
Title: Thiazolidinediones: from peroxisome-proliferator-activatived receptor r (pparr) to anticancer agents.
Edgar S. Diaz-Cruz, Ph.D., 2005
Advisor: Brueggemeier, Robert W
Title: Interrelationships between aromatase and cyclooxygenase-2 and their role in the autocrine and paracrine mechanisms in breast cancer
Ho-Pi Lin , Ph.D., 2005
Advisor: Chen, Ching-Shih
Title: Celecoxib: Its non-cox-2 targets and its anti-cancer effects
Jiuxiang (Julie) Zhu, Ph.D., 2005
Advisor: Chen, Ching-Shih
Title: From celebrex to a novel class of phosphoinositde-dependent kinase-1 (PDK-1) inhibitors for androgen-independent prostate caner [sic]
Jui-Wen Huang, Ph.D., 2005
Advisor: Chen, Ching-Shih
Title: Part I: troglitazone analogues as cyclin d1 ablative agents: the potential drugs for breast cancer therapy. Part 2: vitamin E and its analgues thduce apoptosis in prostate cancer cells in part through inhibition.
Keun-Feng Chen, Ph.D., 2005
Advisor: Chen, Ching-Shih
Title: Troglitazone: from an insulin sensitizer to a novel class of anti-cancer agent.
Manar Salem, Ph.D., 2005
Advisor: Werbovetz, Karl
Title: Identification of antikinetoplastid compounds from Psorothamnus polydenius and P. arborescens.
Ping-Hui Tseng, Ph.D., 2005
Advisor: Chen, Ching-Shih
Title: PDK-1/ Akt pathway as targets for chemosensitizing effects.
Qiang Lu, Ph.D., 2005
Advisor: Chen, Ching-Shih
Title: Potent Short-Chain Fatty Acid-based Histone Deacetylare Inhibitors as Anti-tumor Agents
Serena Landini, M.S., 2005
Advisor: Brueggemeier, Robert W.
Title: Effects of natural and synthetic flavonoids on molecular targets in breast cancer
Yeng-Jeng Shaw, Ph.D., 2005
Advisor: Chen, Ching-Shih
Title: Small Molecule-based Drug Design of Anticancer Agents that Target Protein Kinase B/ AKT, BCL-xL and DNA Methyltransferases for the Treatment of Prostate Cancer
James E. Cox, Ph.D., 2004
Advisor: Priestly/Brueggemeier, Robert W
Title: Characterization of NonR, an esterase that confers nonactin resistance
John C Hackett, Ph.D., 2004
Advisor: Brueggemeier, Robert W
Title: Computational investigations of cytochrome P450 aromatase catalysis and biological evaluation of isoflavone aromatase inhibitors
Joel R. Walker, Ph.D., 2003
Advisor: Curley, Robert W
Title: Part 1. Synthesis of N-15 labeled (R)-deuterioglycine. Part 2. Synthesis of carbon-Linked analogs of retinoid glycoside conjugates
Young-Woo Kim, Ph.D., 2003
Advisor: Brueggemeier, Robert W
Title: Novel 2-substituted isoflavones: a privileged structure approach to new agents for hormone-dependent breast cancer
David J. Lapinsky, Ph.D., 2002
Advisor: Bergmeier/Brueggemeier
Title: Studies in aziridine-allylsilane chemistry
Derek W. Barnett, Ph.D., 2002
Advisor: Curley, Robert W
Title: Part 1. Synthesis of stable-isotope labeled amino acids. Part 2. Synthesis of mechanistic probes of retinoid action
Jennifer Amy Zink, M.S., 2002
Advisor: Li, Pui-Kai
Title: SAR study and mechanism elucidation of thalidomide analogs as anti-proliferative and anti-angiogenic agents
Kristjan M. Arason, Ph.D., 2002
Advisor: Bergmeier, Stephen C
Title: Analogues of methyllycaconitine (MLA) as antagonists of nicotinic receptors
Jennifer L. Whetstone (Windholtz), Ph.D., 2001
Advisor: Brueggemeier, Robert W
Title: Identification of synthetic benzopyranones as selective agents for molecular targets in breast cancer
John Allen Means, Ph.D., 2001
Advisor: Hines/Brueggemeier
Title: Development of assay systems for the study of small molecule interactions with RNA
Jon Howard Baker, Jr., Ph.D., 2001
Advisor: Brueggemeier, Robert W
Title: Biochemical evaluation of benzopyranones : aromatase inhibition and development of a receptor tyrosine kinase assay
Kevin L. Weiss, Ph.D., 2001
Advisor: Curley, Robert W
Title: Structural probes of retinoid action
Linda Huong Rakes, M.S., 2001
Advisor: Robertson, Larry W
Title: Acid-catalyzed rearrangement products of cinchonine : isolation, antimicrobial and transformation studies
Melinda S. Gerdeman (Xavier), Ph.D., 2001
Advisor: Brueggemeier, Robert W
Title: Solution structure and in vitro studies of the antiterminator found in Bacillus Subtilis TYRS mRNA
Michael Eric Nelson, Ph.D., 2001
Advisor: Priestly/Brueggemeier
Title: Nonactin biosynthesis : stable isotope precursor studies
Serena Marie Mershon, M.S., 2001
Advisor: Curley, Robert W
Title: Chemical studies of N-(4-Hydroxyphenyl)retinamide and analogs
Surachai (Shaw) Joomprabutra, Ph.D., 2001
Advisor: Brueggemeier, Robert W
Title: Biological and molecular modeling studies of a benzopyranone library
Abhijit Bhat, Ph.D., 2000
Advisor: Brueggemeier, Robert W.
Title: Part A: Synthesis and Biochemical Evaluation of Estrogen Metabolite Analogs. Part B: Synthetic Approaches for Constructiong a Benzopyrone Combinatorial Library
James Austin Mobley, Ph.d., 2000
Advisor: Brueggemeier, Robert W
Title: Oxidative mechanisms of estrogen induced carcinogenesis
Rosario Rojas, Ph.D., 2000
Advisor: Robertson, Larry W
Title: Secondary metabolites of Vernonia gigantea roots : isolation, antimicrobial, chemical and biotransformation studies
Susan L. Fundy (Donaldson), Ph.D., 2000
Advisor: Bergmeier, Stephen C
Title: Part 1: synthesis and evaluation of Oligo (5-Aminopentanoic Acid)-Nucleobases : Part 2: studies in Aziridine-Allysilane Chemistry
Punit Seth, Ph.D., 1999
Advisor: Bergmeier, Stephen C.
Title: Intramolecular cyclization reactions of Aziridines with Allylsilanes, application to total synthesis of (-)-Yohimbane and Ent-Alloyohimbane
Dionne M. Stanchina, Ph.D., 1998
Advisor: Bergmeier, Stephen C
Title: Acylnitrenes for the synthesis of vicinal amino alcohols : application to the synthesis of (-)-bestatin and analogs
Dionne M. Stanchina, Ph.D., 1998
Advisor: Bergmeier, Stephen C.
Title: Acylnitrenes for the synthesis of vicinal amino alcohols : application to the synthesis of (-)-bestatin and analogs
Panadda Yaipakdee, Ph.D., 1998
Advisor: Robertson, Larry W
Title: Secondary metabolites of Aspergillus Candidus : isolation, chemical, antimicrobial and biotransformation studies
Anne L. Quinn, Ph.D., 1997
Advisor: Brueggemeier, Robert W.
Title: Aromatase expression and enzyme activity in breast cancer
Appavu K. Sundaram, Ph.D., 1997
Advisor: Curley, Robert W.
Title: Chemical and spectroscopic studies on retinoid microbial metabolites and retinoid/protein interactions
Pamela L. Boner, Ph.D., 1997
Advisor: Doskotch, Raymond W.
Title: Isolation and structural studies of natural products of solidago ohioensis riddell, amphiachyris dracunculoides (dc.) nutt., and ageratina colestinum l.
Thomas Gregory Urchek, Ph.D., 1997
Advisor: Olson, Carter L.
Title: The development and application of new instrumentation for mass transport studies
Anthony J. Lunato, Ph.D., 1996
Advisor: Soloway, Albert H.
Title: Part1: Synthesis and in vitro phosphorylation of a homologous series of 5-s-alkylcarboranyl-2'-deoxyuridines and 3-n-alkylcarboranyl- thymidines for use in boron neutron capture therapy of brain cancer: Part 2: an investigation into the stereoselective formation of 3,5-di-0-(p- toluoyl)-2-deoxy-(alpha)-D-ribofuranosyl chloride
Haiyan Pu, M.S., 1996
Advisor: Robertson, Larry W.
Title: Antimicrobial and phytochemical investigation of Bidens Cernua L.
Michael J. Robarge, Ph.D., 1996
Advisor: Curley, Robert W.
Title: Stable analogues of retinoid-O-glucuronides : synthesis and biological activity
Patrick John Ward, Ph.D., 1996
Advisor: Brueggemeier, Robert W.
Title: Development of Steroidal Inhibitors of Cytochrome P450-Dependent Androgen and Estrogen Biosynthesis
Jill Marie O'Reilly, Ph.D., 1995
Advisor: Brueggemeier, Robert W.
Title: Synthesis and Biochemical Evaluation of a New Series of Aromatase Inhibitors: 7(alpha)-Arylaliphatic Androst-4-ene-3,17-diones and 7(alpha)-Arylaliphatic Androsta-1,4-diene-3,17-diones
Luz Minerva Burgos Fuster, M.S., 1995
Advisor: Soloway, Albert H.
Title: Syntheses, characterizations and reactions involved in the preparations of boronated hydantoins
Xiaoyan Zhang , Ph.D., 1995
Advisor: Miller/Brueggemeier
Title: Design, Synthesis and Biological Activities of 4-Substituted Imidazoles as (alpha)2-Adrenoceptor Agonists
Joya Reena Hariharan, M.S., 1994
Advisor: Soloway, Albert H.
Title: Design and synthesis of novel polyamine derivatives for boron neutron capture therapy for cancer
James Edward Romito, Ph.D., 1993
Advisor: Olson, Carter L.
Title: The design and development of a new instrument to monitor mass transport across membranes based on spatially resolved refractive index measurements
Robert Laurence Chapman, Ph.D., 1993
Advisor: Robertson, Larry W.
Title: Biologically active secondary metabolites of the fungus, Aspergillus flavipes
Michael J. Pcolinski, Ph.D., 1992
Advisor: Doskotch, Raymond W.
Title: Structural studies of natural products from Silphium perfoliatum L. Amphiachyris amoena (Shinner's) Solbrig and Amphiachyris dracunculoides DC. Nutt.
Mustapha Ahmed Beleh, Ph.D., 1992
Advisor: Brueggemeier, Robert W.
Title: Protein induction and estrogen metabolism in subcellular preparations and tissue slices of the golden Syrian hamster
Soheila Ebrahimian, Ph.D., 1992
Advisor: Brueggemeier, Robert W.
Title: Synthesis and biochemical evaluation of enzyme-activated irreversible aromatase inhibitors
Shu-Ling Liao, Ph.D., 1991
Advisor: Olson, Carter L.
Title: Part I : Use of a laser/photodiode array system to study transport of 4-nitrophenol across silicone rubber membranes; Part II : A generic microcomputer-based electroanalytical system
David A. Hartman, Ph.D., 1990
Advisor: Curley, Robert W.
Title: The synthesis, stereochemistry, and metabolic significance of ring-hydroxylated retinoids
James M. Chapman, Ph.D., 1990
Advisor: Curley, Robert W.
Title: The preparation and evaluation of immobilized retinoid analogues in the affinity chromatographic purification of retinoid binding proteins
Sanford Len Shew, Ph.D., 1990
Advisor: Olson, Carter L.
Title: Fluorescence lifetime studies of ligand-protein binding using the impulse response technique with refined data analysis methods
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