Park, I. H., Boger, D. L., Wilson, I. A., Olson, A. J. and Li, C. A binding free energy simulation of avian IMP cyclohydrolase in complex with a sulfonyl-containing transition-state nucleoside Analog”, (Manuscript in preparation), 2008.

Lin L., Hutzen B., Ball S., M., Li C., Fuchs J., Li, P-K., and Lin J. Inhibitory effects of curcumin analogues in human breast and pancreaict cancer cells. (Manuscript in preparation), 2008.

Nadas, J., Li, C., and Wang, P. G. Computational Structure Activity Relationship Studies on the CD1d/glycolipid/TCR Complex using AMBER and AUTODOCK. J. Chem. Info. & Modeling., Manuscript in Revision (2008).

Kumari, V. and Li, C. Comparative Docking Assessment of Glucokinase Interactions with Its Allosteric Activators. Current Chemical Genomics, 2008, invited contribution.

Fuh B., Sobo M., Cen L, Sobo M., Josiah D., Hutzen B., Cisek K., Bhasin D., Regan N., Chan C, Caldas  H., Li C., Li P., and Lin J.  LLL-3 inhibits STAT3 activity, suppresses glioblastoma multiforme cell  growth and prolongs survival in a mouse glioblastoma multiforme model.  British Journal of Cancer  2008, Accepted.

Liu, Z.; Xie, Z.; Liu, S.; Pavlovicz, R. E.; Wu, J.; Plass, C.; Li, P.-K.; Li, C.; Huang, T. H.-M.; Marcucci, G. And Chan, K. K. “DNA Methylation Modulation by a Sesquiterpene Lactone Parthenolide”. Journal of Pharmacology and Experimental Therapeutics, 2008, accepted.

Hsu, P.-Y., Liu, H.-S., Li, C., Qin, H., Lai, M.-D., Cheng, H.-L., Tzai, T.-S., Cheng, A. S. L., Davuluri, R. V., Yan, P. S. Huang, T. H.-M. and Chow, N.-H. “Heterologous Interaction Facilitates Nuclear Translocalization of Membranous RON for Modulating Stress-responsive Transcription”, Oncogene, 2008, accepted.

Gonzalez-Cestari, T. F., Henderson, B. J., Pavlovicz, R. E., McKay, S. B., El-Hajj, R. A., Pulipaka, A. B., Orac, C. M., Reed, D. D., Boyd, R. T., Zhu, M. X., Li, C., Bergmeier, S. C. and McKay, D. B. Effect of Novel Negative Allosteric Modulators of Neuronal Nicotinic Receptors on Cells Expressing Native and Recombinant Nicotinic Receptors: Implications for Drug Discovery. Journal of Pharmacology and Experimental Therapeutics, 2008, in press.

Patil, P. N.; Li, C.; Kumari, V. and Hieble, J. P. “Analysis of efficacy of chiral adrenergic agonists”. Chirality 2008, 20, 529-543.

Bhasin, D., Cisek, K., Pandharkar, T., Li, C., Lin, J. and Li, P.-K. “Design, Synthesis and Studies of Small  Molecules STAT3 Inhibitors”, Bioorg. Medicinal. Chem. Lett. 2008, 18, 391-395.

George, T. G.; Endeshaw, M. M.; Morgan, R. E.; Mahasenan, K. V.; Delfín, D. A.; Mukherjee, M. S.; Yakovich, A. J.; Li, C. and Werbovetz, K. A. “Synthesis, Biological Evaluation and molecular modeling  of 3,5-Substituted-N1-phenyl-N4, N4-di-n-butylsulfanilamides as Antikinetoplastid Antimicrotubule Agents”.  Bioorg. Medicinal. Chem. 2007, 15(18), 6071-6079.

Xu, L., Chong, Y., Hwang, I., D'Onofrio, A., Amore, K., Beardsley, G. P., Li, C., Arthur J. Olson, A., Dale L. Boger, D. L. and Wilson, I. A. “Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase”. J. Biol. Chem., 2007, 282: 13033-13046.

Jiang, Z.; Georgel, P.; Li, C.; Choe, J.; Crozat, K.; Rutschmann, S.; Du, X.; Bigby, T.; Mudd, S.; Sovath, S.; Wilson, I. A.; Olson, A. and Beutler B.  “Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis”.  Proc. Nat. Acad. Sci. 2006, 103: 10961-10966.

Pandit, B.; Sun, Y.; Chen, P.; Sackett, D. L.; Hu, Z.; Rich, W.; Li, C.; Lewis, A.; Schaefer, K.; Li, P.-K. "Structure–activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416". Bioorg. Medicinal. Chem. 2006, 14 (19): 6492-6501.

Shiau, C.-W.; Huang, J.-W.; Wang, D.-W.; Weng, J.-R.; Yang, C.-C.; Lin, C.-H., Li, C. and Chen, C.-S. “α-tocopheryl succinate induces apoptosis in prostate cancer cells in part through inhibition of Bcl-xl/Bcl-2 function”.  J. Biol. Chem., 2006, 281: 11819-11825.

Li, P.-K.; Pandit, B.; Sackett, D. L.; Hu, Z.; Zink, J.; Zhi, J.; Freeman, D.; Robey, R. W.; Werbovetz, K.; Lewis, A. and Li, C. “A thalidomide analogue with in vitro antiproliferative, antimitotic, and microtubule-stabilizing activities”. Mol. Cancer Ther. 2006, 5: 450-456.

Fang, L.; Zhang, G.; Li, C.; Zheng, X.; Zhu, L.; Xiao, J. J.; Szakacs, G.; Chan, K. K.; Wang, P. G. and Sun, D. “Discovery of A Daunorubicin Analog That Exhibits Potent Antitumor Activity and Overcomes P-gp-mediated Drug Resistance”. J. Med. Chem., 2006, 49(3); 932-941.

Wu, S.; Xie, P.; Welsh, K.; Li, C.; Ni, C.-Z.; Zhu, X.; Reed, J. C.; Satterthwait, A. C.; Bishop, G. A. and Ely, K. R. “LMP1 Protein from the Epstein-Barr Virus Is a Structural CD40 Decoy in B Lymphocytes for Binding to TRAF3”. J. Biol. Chem., 2005, 280(39): 33620 - 33626.

Santelli, E.; Leone, M.; Li, C.; Fukushima, T.; Preece, N.E.; Olson, A.J.; Ely, K. R.; Reed, J. C.; Pellecchia, M.; Liddington, R. C. and Matsuzawa, S-i. “Structural analysis of Siah1-SIP interactions and insights into the assembly of an E3 ligase multiprotein complex”. J. Biol. Chem., 2005, 280:34278- 34287.

Briknarová, K.; Nasertorabi, F.; Havert, M. L; Eggleston, E; Hoyt, D.W.;Li, C.; Olson, A. J.; Vuori, K. and Ely, K. R.“ The serine-rich domain from Crk-associated substrate (p130Cas) is a four-helix bundle”. J. Biol. Chem., 2005, 280: 21908-21914.

Li, C.; Xu, L.; Wolan, D. W.; Wilson, I. A. and Olson, A. J. “Virtual Screening of Human AICAR Transformylase against the NCI Diversity set Using AutoDock to Identify Novel Non-folate Inhibitors”. J. Med. Chem., 2004, 47(27): 6681-6690.

Xu, L.; Li, C.; Olson, A. J. and Wilson, I.A. “Crystal Structure of Avian AICAR Transformylase in Complex with a Novel Inhibitor Identified by Virtual Ligand Screening”. J. Biol. Chem., 2004, 279: 50555-50565.

Li, C.; Norris, P. S.; Ni, C.-Z.; Havert, M. L.; Chiong, E. M.; Tran, B. R.; Cabezas, E.; Reed, J. C.; Satterthwait, A. C.; Ware, C. F. and Ely, K. R. “Structurally Distinct Recognition Motifs in Lymphotoxin- Receptor and CD40 for Tumor Necrosis Factor Receptor-associated Factor (TRAF)-mediated Signaling”. J. Biol. Chem., 2003, 278: 50523-50529.

Bennett, E.M.; Li, C.; Allen, P. W.; Parker, W.B. and Ealick, S.E. “Structural Basis for Substrate Specificity of Escherichia coli Purine Nucleoside Phosphorylase”. J. Biol. Chem., 2003, 278: 47110-47118.

Zhang, Y.; Desharnais, J.; Marsilje, T. H.; Li, C.; Hedrick, M. P.; Gooljarsingh, L. T.; Tavassoli, A.; Benkovic, S. J.; Olson, A. J.; Boger, D. L. and Wilson, I. A. “Rational Design, Synthesis, Evaluation and Crystal Structure of a Potent Inhibitor of Human GAR Tfase: 10-Trifluoroacetyl-5, 10-Dideaza-Acyclic-5, 6,7,8-Tetrahydrofolic acid”. Biochemistry, 2003, 42(20): 6043-6056.

Ni, C.-Z.; Li, C.; Wu, J. C.; Spada, A. P. and Ely, K. R. “Conformational restrictions in the active site of unliganded human caspase-3”. J. Mol. Recognit. 2003, 16(3):121-4.

Matsuzawa, S-i.; Li, C.; Ni, C.-Z.; Takayama, S.; Reed, J. C. and Ely, K. R. “Structural Analysis of Siah1 and Its Interactions with Siah-interacting Protein (SIP)”. J. Biol. Chem., 2003; 278: 1837 - 1840.

Ely, K. R. and Li, C. “Structurally Adaptive Hot Spots at a Protein Interaction Interface on TRAF3”. J. Mol. Recognit., 2002, 15(5), 286-290.

Li, C.; Havert, M. L.; Cabezas, E.; Satterthwait, A. C.; Ni, C.-Z.; He, J.; Reed, J. C.; Cheng, G. and Ely, K. R. “Downstream Regulator TANK binds to the CD40 Recognition Site on TRAF3”. Structure, March 2002, 10: 403-411.

Li, C.; Kappock, T. J.; Stubbe, J.; Weaver, T. M. and Ealick, S. E. "X-ray Crystal Structure of Aminoimidazole Ribonucleotide Synthetase (PurM) from the Escherichia coli Purine Biosynthetic Pathway at 2.5Å Resolution". Structure, 1999, 7: 1155-1166.

Mueller, E. J.; Oh, S.; Kavalerchik, E.; Kappock, T. J.; Meyer, E.; Li, C.; Ealick, S. E. and Stubbe, J. “Investigation of the ATP Binding Site of Escherichia coli Aminoimidazole Ribonucleotide Synthetase Using Affinity Labeling and Site-Directed Mutagenesis”. Biochemistry, 1999, 38: 9831-9839.

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