Pharmaceutics PhD Degree Curriculum

grad student in lab

A minimum of 54 quarter hour credits of graduate level course work is required for the Ph.D. degree; there is no foreign language requirement.  Flexibility in the program allows students to prepare for a variety of career goals.  This is achieved by requiring every student to take a common core of courses with the remainder of the program consisting of approved electives.  Each student presents one seminar per year, beginning with the second year of study.

Background and Prerequisites

Mathematics through differential equations (Math 255 or the equivalent) is required.

Course work in the statistical analysis of data is required (5 units minimum).  There are multiple pathways by which this requirement may be met.  Courses available at Ohio State include Molecular Genetics 650 (5 units), Statistics 528/529/530 (3/3/3 units), Public Health 701/702/703 (4/4/4 units).

Course work in biological science appropriate to the program of study is required (6 units minimum).  The student selects with the advice of his or her advisor Biochemistry 613/614 (4/4 units), or Molecular Genetics 607/608 (3/3 units).

Course work in physical chemistry is required (6 units minimum): Chemistry 531/532 (3/3 units) or Biochemistry 721.01/721.02 (3/3 units).


grad student
grad student
lab molecule

Program

A. Required of all students:

Seminar Pharmacy 850.01

B. Five courses taught by division faculty from the following list (15-17 units):

Course Name Course Number Units

Advanced Physical Pharmacy

Pharmacy 701 (Frank)

3

Advanced Pharmacokinetics

Pharmacy 802

4

Disposition of Xenobiotics in Biological Systems

Pharmacy 803

3

Drug Transport

Pharmacy 804

3

Controlled Drug Delivery

Pharmacy 805

3

Bioanalytical Methods (lecture; lab)

Pharmacy 806

4,2

Drug Equilibria in Biological Systems

Pharmacy 807

3

Pharmacodynamic Models

Pharmacy 808

3

 

C. Electives, to make a total of at least 54 units of graded graduate level courses. Some possibilities:

Additional Division Courses

Course Name Course Number Units

Biochemistry and Molecular Biology

Biochemistry 615

4

Molecular Genetics: Regulation of Gene Expression

Biochemistry 702

3

Molecular Biology Laboratory

Biochemistry 710

5

Physical Biochemistry

Biochemistry 721.03

3

Proteins

Biochemistry 761

3

Enzymes

Biochemistry 762

2

Membranes and Bioenergetics

Biochemistry 763

2

Advanced Biochemistry: Physical Biochemistry

Biochemistry 765

2

Nucleic Acids

Biochemistry 766

2

Biological Transport

Biomedical Engn. 721

3

Physical Chemistry

Chemistry 533

3

Physical Methods in Organic Chemistry

Chemistry 632

3

Advanced Organic Chemistry I

Chemistry 731

3

Chemical Kinetics I

Chemistry 875

3

Chemical Kinetics II

Chemistry 876

3

Thermodynamics

Chemistry 881

3

Statistical Thermodynamics

Chemistry 882

3

Expository Writing for Graduate Students

English 501

5

Kinetics and Diffusion

Mat. Sci. Engn.

4

Partial Diff. Eqns. and Boundary Value Problems

Mathematics 512

3

Fundamentals of Medical Immunology

Med Micr Immun 701

3

Animal Cell Culture Techniques

Microbiology 655

5

Immunology and Immunochemistry

Microbiology 723.01

3

Immunology and Immunochemistry Lab

Microbiology 723.02

2

Molecular Genetics: DNA Transactions

Molecular Genetics 701

3

Advances in Cell Biology

Molecular Genetics 705

4

Fundamentals of Oncology

Pathology 640

4

General Pharmacology

Pharmacology 600

3

Isolation techniques in Research

Pharmacy 789

5

Principles of Radioisotope Tracer Techniques

Pharmacy 800.01

3

Laboratory in Radioisotope Tracer Techniques

Pharmacy 800.02

2

Advanced Medicinal Chemistry

Pharmacy 835

3

Drug Receptor Theory

Pharmacy 870

3

Organ System Physiology I

Physiology 601

5

Organ System Physiology II

Physiology 602

5

Humane Preparation and Use of Animals ...

Vet Phys 610

3

 

D. Dissertation research, Pharmacy 999, to make a total of 135 units total beyond the baccalaureate degree or 90 units beyond the master's degree.

Committees

Committees involved in each students doctoral program are the Advisory Committee, the Candidacy Examination Committee, the Dissertation Committee, and the Final Oral Examination Committee.  See Section 11 of the College of Pharmacy Graduate Handbook, and Section II.6 of the University Graduate School Handbook for information on the composition and responsibilities of these committees.  All of the committees are composed of the adviser, who must be a Category P graduate faculty member, and at least three or four authorized graduate faculty members who must be either Category M or Category P.  The adviser must be a member of the graduate faculty of the Division of Pharmaceutics and, for the two examination committees, at least one member other than the adviser shall be a regular faculty member with at least a 50% time appointment in the Division of Pharmaceutics (minutes of graduate faculty meeting, May 27, 1993).  The composition of the examination committees must be approved by the Graduate and Research Committee of the college; names of proposed committee members must be submitted to Kathy Brooks’ office at least two weeks before submission of the “Doctoral Notification of Candidacy Examination” form or the “Application to Graduate” form to the graduate school.

Candidacy Examination Policy

The purpose of the candidacy examination is to determine whether graduate students have the preparation and capacity to carry out pharmaceutical research at the doctoral level.  The exam tests for a broad knowledge base in the area of pharmaceutics and the capability for critical thinking about pharmaceutical problems.  This includes the ability of the student to analyze experimental data, to form hypotheses and design experiments to test them, and to critically review the pharmaceutical literature.  The candidacy exam generally does not test recall of specific information presented in course work, although students are presumed to have mastered knowledge and concepts presented in courses.  The candidacy examination should be completed by the end of the third year of full-time study.

The candidacy examination is comprised of a written part and an oral part.  The written part must be passed before the oral part can be taken.

Written Part

The written examination will normally be offered during the last full week of October and of April each year.  Students wishing to take the examination must notify the division chair by the preceding September 15 or March 15 and indicate the faculty members who will make up their written examination committee (see below).  To be eligible to take the examination, students generally should have completed all course work and have a cumulative grade point average of 3.00 or higher.

The written examination for each student will be prepared by the student's adviser and by three additional division faculty who normally will have taught division courses taken by the student.  At least one faculty member other than the student's adviser shall be a regular faculty member with at least a 50% time appointment in the Division of Pharmaceutics.  Each faculty member's part of the examination should require not more than four hours.  When faculty members believe it appropriate, a study guide to focus student preparation for their exam question may be provided.  The examination should be administered within a single week period.

Examination results will be communicated to the student by the examination coordinator three weeks after conclusion of the examination.  A letter grade (A through E, 11 grade system, described under Marks in the OSU Bulletin, Rule 3335-7-21, and in the Graduate School Handbook) will be assigned by each faculty member to the performance on their part of the examination.  The four parts of the examination will have equal weight and the scores for the four parts will be averaged as described under Credit Points and Point-hour Ratio in the Bulletin.  Students achieving an average score of 3.00 (B) or higher will pass the exam; an average score below 3.00 or a grade of E on any of the four parts will constitute failure.  Upon recommendation by the examining faculty, a student failing the written exam will be permitted to retake the exam; the entire exam must be retaken from the original examination committee, and a maximum of two examinations will be allowed.  A second failure of the exam disqualifies a student from advancing to doctoral candidacy status.

Oral Part

The oral part of the examination should be completed by the end of the quarter after which the written part was passed.  This part of the Candidacy Examination will be conducted by the student's Advisory Committee.  At least one member of the committee other than the student's adviser shall be a regular faculty member with at least a 50% time appointment in the Division of Pharmaceutics.  Prior to the examination, the student should prepare a report of background and progress on dissertation research, or an original research proposal unrelated to the dissertation problem, and distribute the report or proposal to the committee. The purpose of the oral exam is to further evaluate, in an oral format, the student's knowledge and capacity for critical thinking about pharmaceutical problems.  Questions from examiners will not be constrained to the dissertation project and the examination should not be solely a defense of the research proposal or the partially completed dissertation research.  The report or proposal may function as a starting point for the examination.  However, any oral presentation of the report or proposal must be made prior to, or after, the oral examination.  Questioning of the student should occupy the entire period of the examination. Upon recommendation by the examining faculty, a student failing the oral exam will be permitted to retake the candidacy exam, at its regularly scheduled offering; a maximum of two examinations will be allowed.  A second failure of the exam disqualifies a student from advancing to doctoral candidacy status.

Graduate School Policy

See Section II.6.9, Graduate School Handbook, for important information about the candidacy examination.

Normal Progress for Graduate Students in Doctoral Program

1.  Students holding half-time associateship appointments are expected to complete an average of 9 units of course work (excluding S/U graded courses) per quarter during the initial quarters of enrollment until their program of study is completed.  Grades of B or better are expected in required courses.

2.  Students are expected to schedule the candidacy examination promptly after completion of course work.  The candidacy examination should be completed by the end of the third year of study.

3.  Students are expected to make progress on their dissertation research.  Evidence of such progress includes publication of papers and abstracts, written research reports, and presentations at local, regional and national scientific meetings.

4.  Students are expected to complete all requirements for the Ph.D. degree within 20 quarters.

5.  Students not making normal progress, determined during the annual review process, will be considered by division faculty at a faculty meeting for reassessment of status in the graduate program.  Possible changes in status include enrollment in the M.S. degree program and/or discontinuation of enrollment.  If the student is supported by division funds (GTA or Fellowship), determination will be made of whether support will be continued.

Pharmaceutics Master of Science Program

The Division of Pharmaceutics does not typically accept students into a Masters of Science Program.  Under special circumstances and with the consent of the Division of Pharmaceutics faculty, students may opt out of the PhD program and pursue a Master of Science degree.


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