Thomas D. Schmittgen, PhD
Recent Publications
Park, J.K., Lee., E.J., Esau, C., and Schmittgen, T.D. Antisense inhibition of microRNA reduces cell viability and sensitizes the effects of gemcitabine in pancreatic cancer. Pancreas, 38: e190-199, 2009.
Nuovo, G.J., Lee, E.J., Lawler, S., Godlewski, J., and Schmittgen, T.D. In situ detection of mature microRNA by ultramer-based extension. Biotechniques, 46:115-126, 2009.
Hunter, M.G., Ismail, N., Zhang, X., Aguda, B.D., Lee, E.J., Yu, L., Xiao, T., Schafer, J., Lee, M.L.T., Schmittgen, T.D., Nana-Sinkam, P., Jarjoura, D., and Marsh, C.B. Identification and characterization of miRNA expression in human peripheral blood microvesicles. PLOS One, 3(11): e3694, 2008.
Jiang, J., Aderca, I., Gusev, Y., Mettler, T.A., Nagorney, D.M., Brackett, D.J., Roberts, L.R. and Schmittgen, T.D. microRNA expression in hepatocellular carcinoma is associated with hepatitis infection, cirrhosis and patient’s survival. Clin. Cancer Res., 14: 419-427, 2008.
MicroRNAs Modulate Chemoresistance of Tumor Cells. Blower, P.E., Chung, J.H., Verducci, J.L., Lin, S., Park, J. K., Dai1, Z., Liu, C.G., Schmittgen, T.D., Croce, C.M., Weinstein, J.N., and Sadee, W. Molec. Cancer Ther., 7: 1-9, 2008.
Lee, E.J., Baek, M., Nuovo, G.J., Chen, C. and Schmittgen, T.D. Systematic evaluation of microRNA processing patterns in tissues, cell lines and tumors. RNA, 14:35-42, 2007.
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Calin, G.A., Liu, C.G., Ferracin, M., Hyslop, T., Sevignani, C., Cimmino, A., Wojcick, S., Shimizu, M., Fabbri, M., Picchiori, F., Lee, E.J., Liu, X., Volta, C., Zuppo, S., Herlea, V., Gramantieri, L., Lanza, G., Alder, H., Schmittgen, T.D., Volinia, S., Rassenti, L., Kipps, T.J., Negrini, M. and Croce, C.M. Ultraconserved regions encoding noncoding RNAs are altered in human leukemias and carcinomas. Cancer Cell, 12:215-229, 2007.
Martin, M.M., Buckenberger, J.A., Jiang, J., Malana, G.E., Feldman, D.S., Schmittgen, T.D., and Elton, T.S. The human angiotensin II type 1 receptor +1166 A/C polymorphism attenuates miR-155 binding. J. Biol. Chem., 282:24262-9, 2007.
Foraker, A.B., Ray, A., Da Silva, C., Bareford, L.M., Hillgren, K.M., Schmittgen, T.D., and Swaan, P.W. Dynamin 2 regulates riboflavin endocytosis in human placental trophoblasts. Molec. Pharmacol., 72:553-562, 2007.
Lee, E.J., Gusev, Y., Jiang, J., Nuovo, G.J., Lerner, M.R., Frankel, W.L., Morgan, D.L., Postier, R.G., Brackett, D.J., Schmittgen, T.D. Expression profiling identifies microRNA signature in pancreatic cancer. Int. J. Cancer, 120:1046-1054, 2007.
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